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mouse dna promoter array  (Arraystar inc)

 
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    Arraystar inc mouse dna promoter array
    Expression of DNMTs and activity of Wnt signaling pathway were increased but Notum expression was decreased in laser-induced CNV mice. ( A – D ) Representative western blot and quantitative analysis of DNMT1, DNMT3A, and DNMT3B in REP/choroidal complexes from the indicated groups ( n = 9 mice/per group for all experiments). ( E – G ) qRT-PCR was performed to detect the mRNA expression of DNMTs in the RPE/choroidal complexes from normal and laser-induced CNV mice ( n = 6 mice/per group for all experiments). ( H ) Clustering of differentially enriched peaks <t>of</t> <t>methylation</t> in the <t>DNA</t> promoter region in the RPE/choroidal complexes from the normal group and the laser-induced CNV group ( red , hypermethylation; green , hypomethylation). ( I ) Enrichment analysis of KEGG pathways and the top 10 activated pathways identified among hypermethylated differentially methylated genes in the RPE/choroidal complexes from the normal group and the laser-induced CNV group. ( J – P ) qRT-PCR was performed to detect the mRNA expression of Wnt signaling-related genes in the RPE/choroidal complexes from the normal group and the laser-induced CNV group ( n = 9 mice/per group for all experiments). Each experiment was repeated at least three times, and data in the graphs represent the mean ± SEM. * P < 0.05; ** P < 0.01; *** P < 0.001.
    Mouse Dna Promoter Array, supplied by Arraystar inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/mouse dna promoter array/product/Arraystar inc
    Average 90 stars, based on 1 article reviews
    mouse dna promoter array - by Bioz Stars, 2026-04
    90/100 stars

    Images

    1) Product Images from "5-Aza-2′-Deoxycytidine Ameliorates Choroidal Neovascularization by Inhibiting the Wnt/β-Catenin Signaling Pathway"

    Article Title: 5-Aza-2′-Deoxycytidine Ameliorates Choroidal Neovascularization by Inhibiting the Wnt/β-Catenin Signaling Pathway

    Journal: Investigative Ophthalmology & Visual Science

    doi: 10.1167/iovs.65.2.23

    Expression of DNMTs and activity of Wnt signaling pathway were increased but Notum expression was decreased in laser-induced CNV mice. ( A – D ) Representative western blot and quantitative analysis of DNMT1, DNMT3A, and DNMT3B in REP/choroidal complexes from the indicated groups ( n = 9 mice/per group for all experiments). ( E – G ) qRT-PCR was performed to detect the mRNA expression of DNMTs in the RPE/choroidal complexes from normal and laser-induced CNV mice ( n = 6 mice/per group for all experiments). ( H ) Clustering of differentially enriched peaks of methylation in the DNA promoter region in the RPE/choroidal complexes from the normal group and the laser-induced CNV group ( red , hypermethylation; green , hypomethylation). ( I ) Enrichment analysis of KEGG pathways and the top 10 activated pathways identified among hypermethylated differentially methylated genes in the RPE/choroidal complexes from the normal group and the laser-induced CNV group. ( J – P ) qRT-PCR was performed to detect the mRNA expression of Wnt signaling-related genes in the RPE/choroidal complexes from the normal group and the laser-induced CNV group ( n = 9 mice/per group for all experiments). Each experiment was repeated at least three times, and data in the graphs represent the mean ± SEM. * P < 0.05; ** P < 0.01; *** P < 0.001.
    Figure Legend Snippet: Expression of DNMTs and activity of Wnt signaling pathway were increased but Notum expression was decreased in laser-induced CNV mice. ( A – D ) Representative western blot and quantitative analysis of DNMT1, DNMT3A, and DNMT3B in REP/choroidal complexes from the indicated groups ( n = 9 mice/per group for all experiments). ( E – G ) qRT-PCR was performed to detect the mRNA expression of DNMTs in the RPE/choroidal complexes from normal and laser-induced CNV mice ( n = 6 mice/per group for all experiments). ( H ) Clustering of differentially enriched peaks of methylation in the DNA promoter region in the RPE/choroidal complexes from the normal group and the laser-induced CNV group ( red , hypermethylation; green , hypomethylation). ( I ) Enrichment analysis of KEGG pathways and the top 10 activated pathways identified among hypermethylated differentially methylated genes in the RPE/choroidal complexes from the normal group and the laser-induced CNV group. ( J – P ) qRT-PCR was performed to detect the mRNA expression of Wnt signaling-related genes in the RPE/choroidal complexes from the normal group and the laser-induced CNV group ( n = 9 mice/per group for all experiments). Each experiment was repeated at least three times, and data in the graphs represent the mean ± SEM. * P < 0.05; ** P < 0.01; *** P < 0.001.

    Techniques Used: Expressing, Activity Assay, Western Blot, Quantitative RT-PCR, Methylation



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    mouse dna promoter array  (Arraystar inc)
    90
    Arraystar inc mouse dna promoter array
    Expression of DNMTs and activity of Wnt signaling pathway were increased but Notum expression was decreased in laser-induced CNV mice. ( A – D ) Representative western blot and quantitative analysis of DNMT1, DNMT3A, and DNMT3B in REP/choroidal complexes from the indicated groups ( n = 9 mice/per group for all experiments). ( E – G ) qRT-PCR was performed to detect the mRNA expression of DNMTs in the RPE/choroidal complexes from normal and laser-induced CNV mice ( n = 6 mice/per group for all experiments). ( H ) Clustering of differentially enriched peaks <t>of</t> <t>methylation</t> in the <t>DNA</t> promoter region in the RPE/choroidal complexes from the normal group and the laser-induced CNV group ( red , hypermethylation; green , hypomethylation). ( I ) Enrichment analysis of KEGG pathways and the top 10 activated pathways identified among hypermethylated differentially methylated genes in the RPE/choroidal complexes from the normal group and the laser-induced CNV group. ( J – P ) qRT-PCR was performed to detect the mRNA expression of Wnt signaling-related genes in the RPE/choroidal complexes from the normal group and the laser-induced CNV group ( n = 9 mice/per group for all experiments). Each experiment was repeated at least three times, and data in the graphs represent the mean ± SEM. * P < 0.05; ** P < 0.01; *** P < 0.001.
    Mouse Dna Promoter Array, supplied by Arraystar inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/mouse dna promoter array/product/Arraystar inc
    Average 90 stars, based on 1 article reviews
    mouse dna promoter array - by Bioz Stars, 2026-04
    90/100 stars
    		  Buy from Supplier
    mouse brain genome-wide promoter dna methylation array  (Illumina Inc)
    90
    Illumina Inc mouse brain genome-wide promoter dna methylation array
    Expression of DNMTs and activity of Wnt signaling pathway were increased but Notum expression was decreased in laser-induced CNV mice. ( A – D ) Representative western blot and quantitative analysis of DNMT1, DNMT3A, and DNMT3B in REP/choroidal complexes from the indicated groups ( n = 9 mice/per group for all experiments). ( E – G ) qRT-PCR was performed to detect the mRNA expression of DNMTs in the RPE/choroidal complexes from normal and laser-induced CNV mice ( n = 6 mice/per group for all experiments). ( H ) Clustering of differentially enriched peaks <t>of</t> <t>methylation</t> in the <t>DNA</t> promoter region in the RPE/choroidal complexes from the normal group and the laser-induced CNV group ( red , hypermethylation; green , hypomethylation). ( I ) Enrichment analysis of KEGG pathways and the top 10 activated pathways identified among hypermethylated differentially methylated genes in the RPE/choroidal complexes from the normal group and the laser-induced CNV group. ( J – P ) qRT-PCR was performed to detect the mRNA expression of Wnt signaling-related genes in the RPE/choroidal complexes from the normal group and the laser-induced CNV group ( n = 9 mice/per group for all experiments). Each experiment was repeated at least three times, and data in the graphs represent the mean ± SEM. * P < 0.05; ** P < 0.01; *** P < 0.001.
    Mouse Brain Genome Wide Promoter Dna Methylation Array, supplied by Illumina Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/mouse brain genome-wide promoter dna methylation array/product/Illumina Inc
    Average 90 stars, based on 1 article reviews
    mouse brain genome-wide promoter dna methylation array - by Bioz Stars, 2026-04
    90/100 stars
    		  Buy from Supplier

    Image Search Results


    Expression of DNMTs and activity of Wnt signaling pathway were increased but Notum expression was decreased in laser-induced CNV mice. ( A – D ) Representative western blot and quantitative analysis of DNMT1, DNMT3A, and DNMT3B in REP/choroidal complexes from the indicated groups ( n = 9 mice/per group for all experiments). ( E – G ) qRT-PCR was performed to detect the mRNA expression of DNMTs in the RPE/choroidal complexes from normal and laser-induced CNV mice ( n = 6 mice/per group for all experiments). ( H ) Clustering of differentially enriched peaks of methylation in the DNA promoter region in the RPE/choroidal complexes from the normal group and the laser-induced CNV group ( red , hypermethylation; green , hypomethylation). ( I ) Enrichment analysis of KEGG pathways and the top 10 activated pathways identified among hypermethylated differentially methylated genes in the RPE/choroidal complexes from the normal group and the laser-induced CNV group. ( J – P ) qRT-PCR was performed to detect the mRNA expression of Wnt signaling-related genes in the RPE/choroidal complexes from the normal group and the laser-induced CNV group ( n = 9 mice/per group for all experiments). Each experiment was repeated at least three times, and data in the graphs represent the mean ± SEM. * P < 0.05; ** P < 0.01; *** P < 0.001.

    Journal: Investigative Ophthalmology & Visual Science

    Article Title: 5-Aza-2′-Deoxycytidine Ameliorates Choroidal Neovascularization by Inhibiting the Wnt/β-Catenin Signaling Pathway

    doi: 10.1167/iovs.65.2.23

    Figure Lengend Snippet: Expression of DNMTs and activity of Wnt signaling pathway were increased but Notum expression was decreased in laser-induced CNV mice. ( A – D ) Representative western blot and quantitative analysis of DNMT1, DNMT3A, and DNMT3B in REP/choroidal complexes from the indicated groups ( n = 9 mice/per group for all experiments). ( E – G ) qRT-PCR was performed to detect the mRNA expression of DNMTs in the RPE/choroidal complexes from normal and laser-induced CNV mice ( n = 6 mice/per group for all experiments). ( H ) Clustering of differentially enriched peaks of methylation in the DNA promoter region in the RPE/choroidal complexes from the normal group and the laser-induced CNV group ( red , hypermethylation; green , hypomethylation). ( I ) Enrichment analysis of KEGG pathways and the top 10 activated pathways identified among hypermethylated differentially methylated genes in the RPE/choroidal complexes from the normal group and the laser-induced CNV group. ( J – P ) qRT-PCR was performed to detect the mRNA expression of Wnt signaling-related genes in the RPE/choroidal complexes from the normal group and the laser-induced CNV group ( n = 9 mice/per group for all experiments). Each experiment was repeated at least three times, and data in the graphs represent the mean ± SEM. * P < 0.05; ** P < 0.01; *** P < 0.001.

    Article Snippet: In this study, the Arraystar Mouse DNA Promoter Array was utilized to determine methylation profiles in the whole genome in the DNA promoters of the RPE/choroidal complex in mice 7 days after laser photocoagulation because the optimum time point to assess CNV formation is typically at day 7 to day 14.

    Techniques: Expressing, Activity Assay, Western Blot, Quantitative RT-PCR, Methylation